L6 · CELL-LINE · Rattus norvegicus
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L6
Review this target as L6.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats L6 as ChEMBL target CHEMBL614793. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | L6 |
| Target Type | CELL-LINE |
| Organism | Rattus norvegicus |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as L6.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL61 | 9.0 | IC50 | 1.0 | Approved |
| CHEMBL228368 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL1477 | 8.77 | IC50 | 1.7 | Approved |
| CHEMBL3234764 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL228637 | 8.6 | IC50 | 2.5 | Preclinical |
| CHEMBL221399 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL2430018 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL231386 | 8.37 | IC50 | 4.3 | Preclinical |
| CHEMBL468204 | 8.31 | IC50 | 4.9 | Preclinical |
| CHEMBL38943 | 8.22 | EC50 | 6.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 298 | 3,110 | 4.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 254 | 350 | 5.7 |
| organism-based format | 13 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 34 | 658 | 4.5 |