Cyclin-dependent kinase 14 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O94921. Use UniProt O94921 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O94921 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-dependent kinase 14
Review this target as Cyclin-dependent kinase 14, mapped to UniProt O94921. Sequence length is 469 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclin-dependent kinase 14 as ChEMBL target CHEMBL6162, mapped to UniProt O94921. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cyclin-dependent kinase 14 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O94921 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-dependent kinase 14 |
| UniProt Accession | O94921 |
| Component Type | Protein |
| Sequence Length | 469 aa |
Cyclin-dependent kinase 14
Review this target as Cyclin-dependent kinase 14, mapped to UniProt O94921. Sequence length is 469 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL384304 | 7.96 | Kd | 11.0 | Clinical |
| CHEMBL445813 | 7.8 | Kd | 16.0 | Clinical |
| CHEMBL574738 | 7.77 | Kd | 17.0 | Preclinical |
| CHEMBL1230609 | 7.51 | Kd | 31.0 | Clinical |
| CHEMBL4580787 | 7.41 | IC50 | 39.0 | Preclinical |
| CHEMBL4522598 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL4542127 | 7.3 | IC50 | 50.0 | Preclinical |
| CHEMBL428690 | 6.96 | Kd | 110.0 | Clinical |
| CHEMBL5423601 | 6.81 | IC50 | 155.2 | Preclinical |
| CHEMBL388978 | 6.8 | Kd | 160.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 70 | 25 | 6.4 |
| assay format | 17 | 1 | 7.1 |
| subcellular format | 14 | 0 | — |
| cell-based format | 10 | 8 | 6.4 |