Serine/threonine-protein kinase LATS1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt O95835. Use UniProt O95835 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O95835 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase LATS1
Review this target as Serine/threonine-protein kinase LATS1, mapped to UniProt O95835. Sequence length is 1130 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase LATS1 as ChEMBL target CHEMBL6167, mapped to UniProt O95835. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein kinase LATS1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95835 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase LATS1 |
| UniProt Accession | O95835 |
| Component Type | Protein |
| Sequence Length | 1130 aa |
Serine/threonine-protein kinase LATS1
Review this target as Serine/threonine-protein kinase LATS1, mapped to UniProt O95835. Sequence length is 1130 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4439972 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL4447153 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL4525078 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL4463018 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL4463415 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL4443335 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4444109 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4446730 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4450439 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4450447 | 9.0 | IC50 | 1.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 94 | 296 | 7.8 |
| cell-based format | 33 | 0 | — |
| assay format | 24 | 44 | 7.9 |
| subcellular format | 21 | 29 | 6.2 |