Use UniProt O95870 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6168 Target Snapshot
Phosphatidylserine lipase ABHD16A · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O95870. Use UniProt O95870 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylserine lipase ABHD16A
Review this target as Phosphatidylserine lipase ABHD16A, mapped to UniProt O95870. Sequence length is 558 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Phosphatidylserine lipase ABHD16A as ChEMBL target CHEMBL6168, mapped to UniProt O95870. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Phosphatidylserine lipase ABHD16A is the right protein anchor across sources, using UniProt O95870 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Phosphatidylserine lipase ABHD16A |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O95870 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylserine lipase ABHD16A |
| UniProt Accession | O95870 |
| Component Type | Protein |
| Sequence Length | 558 aa |
Phosphatidylserine lipase ABHD16A
How to read this target
Review this target as Phosphatidylserine lipase ABHD16A, mapped to UniProt O95870. Sequence length is 558 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL175247 | 7.52 | IC50 | 30.0 | Approved |
| CHEMBL4564841 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL1673415 | 7.24 | IC50 | 57.0 | Preclinical |
| CHEMBL5532498 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL4525638 | 7.05 | IC50 | 90.0 | Preclinical |
| CHEMBL4585683 | 5.47 | IC50 | 3400.0 | Preclinical |
| CHEMBL4591378 | 5.31 | IC50 | 4900.0 | Preclinical |
| CHEMBL158897 | 4.64 | IC50 | 23000.0 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 13 assays, 12 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 11 | 8 | 6.2 |
| single protein format | 2 | 4 | 7.1 |