Lysine-specific demethylase 4C · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9H3R0. Use UniProt Q9H3R0 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9H3R0 as the stable identity anchor, then attach disease evidence before program review.
Lysine-specific demethylase 4C
Review this target as Lysine-specific demethylase 4C, mapped to UniProt Q9H3R0. Sequence length is 1056 aa.
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This review treats Lysine-specific demethylase 4C as ChEMBL target CHEMBL6175, mapped to UniProt Q9H3R0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Lysine-specific demethylase 4C |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9H3R0 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysine-specific demethylase 4C |
| UniProt Accession | Q9H3R0 |
| Component Type | Protein |
| Sequence Length | 1056 aa |
Lysine-specific demethylase 4C
Review this target as Lysine-specific demethylase 4C, mapped to UniProt Q9H3R0. Sequence length is 1056 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5815580 | 9.26 | IC50 | 0.55 | Preclinical |
| CHEMBL5910955 | 9.26 | IC50 | 0.55 | Preclinical |
| CHEMBL4216044 | 8.89 | EC50 | 1.3 | Preclinical |
| CHEMBL316034 | 8.66 | Ki | 2.2 | Preclinical |
| CHEMBL4204694 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL5203487 | 8.66 | IC50 | 2.2 | Preclinical |
| CHEMBL4225358 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL4211946 | 8.22 | IC50 | 6.0 | Preclinical |
| CHEMBL1517074 | 8.1 | IC50 | 8.0 | Preclinical |
| CHEMBL4207583 | 8.1 | IC50 | 8.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 78 | 967 | 6.0 |
| cell-based format | 20 | 314 | 6.2 |
| assay format | 18 | 87 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 1 | 7.4 |