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Target Snapshot

CHEMBL6176 Target Snapshot

NAD kinase · SINGLE PROTEIN · Mycobacterium tuberculosis

15Compounds
3Assays
0Approved Drugs
9.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P9WHV7. Use UniProt P9WHV7 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P9WHV7 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats NAD kinase as ChEMBL target CHEMBL6176, mapped to UniProt P9WHV7. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
NAD kinase
SINGLE PROTEIN · Mycobacterium tuberculosis
As of 2026-09-14
ChEMBL target ID
CHEMBL6176
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P9WHV7
NAD kinase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether NAD kinase is the right protein anchor across sources, using UniProt P9WHV7 as the stable mapping.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelNAD kinase
UniProt AccessionP9WHV7
Component TypeProtein
Sequence Length307 aa

NAD kinase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as NAD kinase, mapped to UniProt P9WHV7. Sequence length is 307 aa.

Mapped IDP9WHV7
Review nameNAD kinase
OrganismMycobacterium tuberculosis
Assay Mix

Activity Type Distribution

IC509.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL560315 4.85 IC50 14000.0 Preclinical
CHEMBL562056 4.72 IC50 19000.0 Preclinical
CHEMBL561654 4.35 IC50 45000.0 Preclinical
CHEMBL559921 4.1 IC50 80000.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

3
Total Assays
6
Tested Compounds
1
Assay Types
Binding — 3 assays, 6 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 3 6 4.5

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine