Use UniProt Q72502 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL6181 Target Snapshot
Envelope glycoprotein gp160 · SINGLE PROTEIN · Human immunodeficiency virus 1
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As of 2026-09-14Protein identity stays anchored to UniProt Q72502. Use UniProt Q72502 as the stable identity anchor, then attach disease evidence before program review.
Envelope glycoprotein gp160
Review this target as Envelope glycoprotein gp160, mapped to UniProt Q72502. Sequence length is 854 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Envelope glycoprotein gp160 as ChEMBL target CHEMBL6181, mapped to UniProt Q72502. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Envelope glycoprotein gp160 is the right protein anchor across sources, using UniProt Q72502 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Envelope glycoprotein gp160 |
| Target Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
| UniProt | Q72502 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Envelope glycoprotein gp160 |
| UniProt Accession | Q72502 |
| Component Type | Protein |
| Sequence Length | 854 aa |
Envelope glycoprotein gp160
How to read this target
Review this target as Envelope glycoprotein gp160, mapped to UniProt Q72502. Sequence length is 854 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4281745 | 8.8 | IC50 | 1.58 | Preclinical |
| CHEMBL4289957 | 8.61 | IC50 | 2.48 | Preclinical |
| CHEMBL440999 | 6.68 | IC50 | 209.4 | Preclinical |
| CHEMBL5413691 | 6.17 | Kd | 670.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 20 assays, 4 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 14 | 1 | 6.2 |
| assay format | 4 | 0 | — |
| cell-based format | 2 | 3 | 8.0 |