Assay Detail

CHEMBL1000048

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Binding

Inhibition of H(+)/K(+) ATPase from pig gastric mucosa

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Sus scrofa
Tissue	Gastric mucosa
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Inhibitory effect of tannic acid on gastric H+,K(+)-ATPase.

Murakami S, Muramatsu M, Otomo S.
J Nat Prod (1992) 55 : 513 -516
PubMed 1324983 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	7.11	7.54

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL506247	TANNIC ACID	4.0	1	7.54
CHEMBL6246	ELLAGIC ACID	2.0	1	6.68

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL506247	TANNIC ACID	IC50	=	29.0	nM	7.54
CHEMBL6246	ELLAGIC ACID	IC50	=	210.0	nM	6.68