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Assay Detail

CHEMBL1000247

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antialagal activity against Chlorella vulgaris Beji assessed as reduction in chlorophyll content after 7 days
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Chlorella vulgaris
Confidence 1 — Organism
Curated By Autocuration

Target

Chlorella vulgaris (CHEMBL613342)
Type ORGANISM
Organism Chlorella vulgaris

Publication

Synthesis and antimycobacterial evaluation of substituted pyrazinecarboxamides.
Dolezal M, Dolezal M, Cmedlova P, Palek L, Vinsova J, Kunes J, Buchta V, Jampilek J, Kralova K.
Eur J Med Chem (2008) 43 : 1105 -1113
PubMed 17870211 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 6 4.60 5.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278489 DCMU 1 5.14
CHEMBL496348 1 4.92
CHEMBL496182 1 4.49
CHEMBL498408 1 4.48
CHEMBL496349 1 4.43
CHEMBL454549 1 4.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278489 DCMU IC50 = 7300.0 nM 5.14
CHEMBL496348 IC50 = 12100.0 nM 4.92
CHEMBL496182 IC50 = 32300.0 nM 4.49
CHEMBL498408 IC50 = 32900.0 nM 4.48
CHEMBL496349 IC50 = 37400.0 nM 4.43
CHEMBL454549 IC50 = 70900.0 nM 4.15