Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL1001111

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Induction of apoptosis in human HL60 cells by flow cytometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Design, synthesis and biological evaluation of novel stilbene-based antitumor agents.
Simoni D, Invidiata FP, Eleopra M, Marchetti P, Rondanin R, Baruchello R, Grisolia G, Tripathi A, Kellogg GE, Durrant D, Lee RM.
Bioorg Med Chem (2009) 17 : 512 -522
PubMed 19117761 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 7.52 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL490294 1 7.52
CHEMBL116888 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL490294 IC50 = 30.0 nM 7.52
CHEMBL116888 IC50 = 30.0 nM 7.52