HL-60 · CELL-LINE · Homo sapiens
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HL-60
Review this target as HL-60.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HL-60 as ChEMBL target CHEMBL383. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | HL-60 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as HL-60.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2158589 | 10.92 | IC50 | 0.012 | Preclinical |
| CHEMBL220846 | 10.74 | EC50 | 0.018 | Preclinical |
| CHEMBL1254818 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL58 | 10.62 | IC50 | 0.024 | Approved |
| CHEMBL2158588 | 10.6 | IC50 | 0.025 | Preclinical |
| CHEMBL511905 | 10.59 | IC50 | 0.0255 | Preclinical |
| CHEMBL466907 | 10.59 | IC50 | 0.026 | Preclinical |
| CHEMBL449897 | 10.58 | IC50 | 0.0263 | Preclinical |
| CHEMBL466909 | 10.58 | IC50 | 0.0266 | Preclinical |
| CHEMBL466908 | 10.56 | IC50 | 0.0275 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6,589 | 9,536 | 5.7 |
| organism-based format | 54 | 0 | — |
| assay format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 125 | 180 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 26 | 16 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 19 | 2 | 4.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 0 | — |