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Assay Detail

CHEMBL1002681

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus (CHEMBL613758)
Type ORGANISM
Organism Human immunodeficiency virus

Publication

Antiviral activity of lignans.
Charlton JL.
J Nat Prod (1998) 61 : 1447 -1451
PubMed 9834179 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.39 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL515928 GOMISIN G 1 7.96
CHEMBL513752 KADSURANIN 1 5.70
CHEMBL437412 SCHISANDRIN C 1 5.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL515928 GOMISIN G IC50 = 11.0 nM 7.96
CHEMBL513752 KADSURANIN IC50 = 2000.0 nM 5.70
CHEMBL437412 SCHISANDRIN C IC50 = 3100.0 nM 5.51