Assay Detail
Binding
CHEMBL1002720
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of fetal bovine serum AChE
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.47 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL32823 | — | — | 1 | 8.89 |
| CHEMBL367067 | — | — | 1 | 8.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL32823 | — | Ki | = | 1.3 | nM | 8.89 |
| CHEMBL367067 | — | Ki | = | 9.1 | nM | 8.04 |