Assay Detail
Binding
CHEMBL1003622
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Inhibition of MMP9
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Current perspective of TACE inhibitors: a review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.77 | 10.21 |
| IC50 | 1 | 7.64 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL61193 | — | — | 1 | 10.21 |
| CHEMBL455409 | — | — | 1 | 7.64 |
| CHEMBL100570 | — | — | 1 | 7.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL61193 | — | Ki | = | 0.061 | nM | 10.21 |
| CHEMBL455409 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL100570 | — | Ki | = | 46.7 | nM | 7.33 |