Assay Detail
Binding
CHEMBL1003630
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Inhibition of MMP1
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Current perspective of TACE inhibitors: a review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.29 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL516206 | — | — | 1 | 8.22 |
| CHEMBL207729 | — | — | 1 | 8.18 |
| CHEMBL18614 | — | — | 1 | 6.94 |
| CHEMBL491287 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL516206 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL207729 | — | IC50 | = | 6.6 | nM | 8.18 |
| CHEMBL18614 | — | IC50 | = | 114.0 | nM | 6.94 |
| CHEMBL491287 | — | IC50 | = | 1600.0 | nM | 5.80 |