Assay Detail
Binding
CHEMBL1003883
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human PDE4C
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
3',5'-cyclic-AMP phosphodiesterase 4C (CHEMBL291) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.62 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL19449 | IBUDILAST | 4.0 | 1 | 6.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL19449 | IBUDILAST | IC50 | = | 239.0 | nM | 6.62 |