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Assay Detail

CHEMBL1003885

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of fMLP-induced LTB4 biosynthesis in human whole blood
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Tissue Blood
Confidence 1 — Organism
Curated By Autocuration

Target

Blood (CHEMBL613416)
Type TISSUE
Organism Homo sapiens

Publication

Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
Kodimuthali A, Jabaris SS, Pal M.
J Med Chem (2008) 51 : 5471 -5489
PubMed 18686943 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.60 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL19449 IBUDILAST 4.0 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL19449 IBUDILAST IC50 = 2500.0 nM 5.60