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Target Snapshot

CHEMBL613416 Target Snapshot

Blood · TISSUE · Homo sapiens

2,148Compounds
479Assays
16Approved Drugs
2,222.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Blood as ChEMBL target CHEMBL613416. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Blood
TISSUE · Homo sapiens
As of 2026-09-13
ChEMBL target ID
CHEMBL613416
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Blood still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

Jump to Disease Context
Need a meeting-ready explanation of why this target matters?
Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelBlood
UniProt AccessionN/A

Blood

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Blood.

Review nameBlood
OrganismHomo sapiens
Clinical Profile

Clinical Phase Distribution

16
Approved
3
Phase III
15
Phase II
3
Phase I
Assay Mix

Activity Type Distribution

IC502,103.0
KI1.0
EC50118.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL5419663 10.05 EC50 0.09 Preclinical
CHEMBL452578 9.92 IC50 0.12 Preclinical
CHEMBL462150 9.9 IC50 0.1259 Preclinical
CHEMBL323312 9.52 IC50 0.3 Preclinical
CHEMBL516978 9.38 IC50 0.42 Preclinical
CHEMBL32442 9.17 IC50 0.67 Preclinical
CHEMBL3417770 9.15 EC50 0.7 Preclinical
CHEMBL495492 9.15 IC50 0.7 Preclinical
CHEMBL327959 9.15 IC50 0.7 Preclinical
CHEMBL327746 9.15 IC50 0.7 Preclinical
Distribution

pChEMBL Value Distribution

206
5.0
259
5.5
322
6.0
303
6.5
170
7.0
78
7.5
62
8.0
40
8.5
13
9.0
5
9.5
pChEMBL
Approved Drugs

Approved Drugs

DEUCRAVACITINIB
CHEMBL4435170
Approved 2022
APREMILAST
CHEMBL514800
Approved 2014
ROFLUMILAST
CHEMBL193240
Approved 2010
FLUTICASONE FUROATE
CHEMBL1676
Approved 2007
BUDESONIDE
CHEMBL1370
Approved 1994
FLUTICASONE PROPIONATE
CHEMBL1473
Approved 1990
INDOMETHACIN
CHEMBL6
Approved 1965
DEXAMETHASONE
CHEMBL384467
Approved 1958
PREDNISOLONE
CHEMBL131
Approved 1955
Assay Landscape

Assay Landscape

479
Total Assays
1,412
Tested Compounds
3
Assay Types
Functional — 351 assays, 1,412 compounds
BAO Format Assays Compounds Avg pChEMBL
tissue-based format 334 1,363 6.3
assay format 6 34 6.4
cell membrane format 5 0
organism-based format 4 5 7.4
cell-based format 2 10 8.3
ADME — 126 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 81 0
tissue-based format 36 0
assay format 9 0
Toxicity — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 0
tissue-based format 1 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine