Assay Detail
Functional
CHEMBL1004268
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Cytotoxicity against mouse LMM3 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | LMM3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Indole alkaloids from the tunicate Aplidium meridianum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.85 | 5.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL44541 | MERIDIANIN C | — | 1 | 5.03 |
| CHEMBL296682 | MERIDIANIN E | — | 1 | 4.96 |
| CHEMBL44545 | MERIDIANIN B | — | 1 | 4.94 |
| CHEMBL46440 | MERIDIANIN D | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL44541 | MERIDIANIN C | IC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL296682 | MERIDIANIN E | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL44545 | MERIDIANIN B | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL46440 | MERIDIANIN D | IC50 | = | 33900.0 | nM | 4.47 |