Assay Detail
Functional
CHEMBL1005113
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Cytotoxicity against mouse EN2 cells after 24 hrs by cell-count assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | EN2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Stereochemistry-dependent cytotoxicity of some artemisinin derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.28 | 6.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL498923 | — | — | 1 | 6.27 |
| CHEMBL504767 | — | — | 1 | 5.05 |
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL498923 | — | IC50 | = | 540.0 | nM | 6.27 |
| CHEMBL504767 | — | IC50 | = | 8900.0 | nM | 5.05 |
| CHEMBL269671 | ARTEMISININ | IC50 | = | 30000.0 | nM | 4.52 |