Assay Detail
Functional
CHEMBL1005118
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anthelmintic activity against Nippostrongylus brasiliensis L4 parasitant on day 5 by double serial dilution model
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Nippostrongylus brasiliensis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Nippostrongylus brasiliensis (CHEMBL613822) ↗| Type | ORGANISM |
| Organism | Nippostrongylus brasiliensis |
Publication
A new indole derivative from the red alga Chondria atropurpurea. Isolation, structure determination, and anthelmintic activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 4.05 | 4.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL456733 | CHONDRIAMIDE C | — | 1 | 4.05 |
| CHEMBL45669 | CHONDRIAMIDE A | — | 1 | - |
| CHEMBL515197 | — | — | 1 | - |
| CHEMBL456734 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL456733 | CHONDRIAMIDE C | EC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL45669 | CHONDRIAMIDE A | EC50 | = | 260000.0 | nM | - |
| CHEMBL515197 | — | EC50 | = | 300000.0 | nM | - |
| CHEMBL456734 | — | EC50 | = | 2370000.0 | nM | - |