Compound Detail
CHEMBL456733
CHONDRIAMIDE C Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL456733 |
| Name | CHONDRIAMIDE C |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UEIGNTNIVBVSQQ-PVHUKWJHSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
327.4
MW (Da)
4.45
ALogP
1
HBA
3
HBD
60.7
PSA (Ų)
0.48
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.05
IC50 1 meas. best 6.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human alphaherpesvirus 2 CHEMBL370 | IC50 | 6.0 | 6.0 | 1000.0 | 1 |
| Nippostrongylus brasiliensis CHEMBL613822 | EC50 | 4.05 | 4.05 | 90000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human alphaherpesvirus 2 | IC50 | = | 1000.0 | nM | 6.0 | Antiviral activity against Herpes simplex virus type 2 | 25462257 |
| Nippostrongylus brasiliensis | EC50 | = | 90000.0 | nM | 4.05 | Anthelmintic activity against Nippostrongylus brasiliensis L4 parasitant on day ... | 9868166 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9868166 | 10.1021/np980114c | Nippostrongylus brasiliensis | 1 |
| 25462257 | 10.1016/j.ejmech.2014.10.065 | Human alphaherpesvirus 2 | 1 |
Data from ChEMBL 36 via Core Engine