Assay Detail
ADMET
CHEMBL1005281
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Cytotoxicity against p-glycoprotein overexpressing CHO cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Two bioactive pterocarpans from Erythrina burana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.26 | 5.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL454849 | ERYTHRABYSSIN I | — | 1 | 5.40 |
| CHEMBL508534 | PHASEOLLIDIN | — | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL454849 | ERYTHRABYSSIN I | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL508534 | PHASEOLLIDIN | IC50 | = | 7600.0 | nM | 5.12 |