Assay Detail
Binding
CHEMBL1005628
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Inhibition of pig pancreatic elastase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Kempopeptins A and B, serine protease inhibitors with different selectivity profiles from a marine cyanobacterium, Lyngbya sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.52 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL398726 | LYNGBYASTATIN 7 | — | 1 | 5.60 |
| CHEMBL450713 | KEMPOPEPTIN A | — | 1 | 5.58 |
| CHEMBL399107 | SOMAMIDE B | — | 1 | 5.38 |
| CHEMBL505477 | KEMPOPEPTIN B | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL398726 | LYNGBYASTATIN 7 | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL450713 | KEMPOPEPTIN A | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL399107 | SOMAMIDE B | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL505477 | KEMPOPEPTIN B | IC50 | > | 67000.0 | nM | - |