Assay Detail
Functional
CHEMBL1006052
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Cytotoxicity against human HL60
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A labdane diterpene glucoside from the rhizomes of Curcuma mangga.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.71 | 5.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL512317 | ZERUMIN B | — | 1 | 5.14 |
| CHEMBL179512 | DEMETHOXYCURCUMIN | — | 1 | 4.62 |
| CHEMBL105350 | BISDEMETHOXYCURCUMIN | — | 1 | 4.60 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.47 |
| CHEMBL71851 | SCOPOLETIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL512317 | ZERUMIN B | IC50 | = | 7210.0 | nM | 5.14 |
| CHEMBL179512 | DEMETHOXYCURCUMIN | IC50 | = | 24210.0 | nM | 4.62 |
| CHEMBL105350 | BISDEMETHOXYCURCUMIN | IC50 | = | 25120.0 | nM | 4.60 |
| CHEMBL140 | CURCUMIN | IC50 | = | 34220.0 | nM | 4.47 |
| CHEMBL71851 | SCOPOLETIN | IC50 | > | 50000.0 | nM | - |