Assay Detail
Binding
CHEMBL1006985
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]PGF2 alpha from FP receptor in bovine corpus luteum membrane
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Tissue | Corpus luteum |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of 13-oxa prostaglandin analogs as antiglaucoma agents: synthesis and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 8 | 6.87 | 7.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL491667 | — | — | 1 | 7.14 |
| CHEMBL491475 | — | — | 1 | 7.06 |
| CHEMBL1050 | LATANOPROST ACID | -1.0 | 1 | 7.01 |
| CHEMBL523143 | — | — | 1 | 6.92 |
| CHEMBL521964 | — | — | 1 | 6.89 |
| CHEMBL815 | DINOPROST | 4.0 | 1 | 6.89 |
| CHEMBL489109 | — | — | 1 | 6.85 |
| CHEMBL491474 | — | — | 1 | 6.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL491667 | — | Ki | = | 72.0 | nM | 7.14 |
| CHEMBL491475 | — | Ki | = | 87.0 | nM | 7.06 |
| CHEMBL1050 | LATANOPROST ACID | Ki | = | 98.0 | nM | 7.01 |
| CHEMBL523143 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL521964 | — | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL815 | DINOPROST | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL489109 | — | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL491474 | — | Ki | = | 680.0 | nM | 6.17 |