Assay Detail
Binding
CHEMBL1007614
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Inhibition of yeast alpha-glucosidase by spectrophotometry
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Glycosidase-inhibiting pyrrolidines and pyrrolizidines with a long side chain in Scilla peruviana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.66 | 5.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL498968 | — | — | 1 | 5.44 |
| CHEMBL512479 | — | — | 1 | 5.18 |
| CHEMBL469429 | — | — | 1 | 4.02 |
| CHEMBL449851 | — | — | 1 | 4.00 |
| CHEMBL511823 | — | — | 1 | - |
| CHEMBL469435 | — | — | 1 | - |
| CHEMBL469437 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL498968 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL512479 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL469429 | — | IC50 | = | 95000.0 | nM | 4.02 |
| CHEMBL449851 | — | IC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL511823 | — | IC50 | = | 630000.0 | nM | - |
| CHEMBL469435 | — | IC50 | = | 220000.0 | nM | - |
| CHEMBL469437 | — | IC50 | = | 650000.0 | nM | - |