Assay Detail
Binding
CHEMBL1007616
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Inhibition of Caldocellum saccharolyticum beta-glucosidase by spectrophotometry
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Caldicellulosiruptor saccharolyticus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Glycosidase-inhibiting pyrrolidines and pyrrolizidines with a long side chain in Scilla peruviana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.51 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL469435 | — | — | 1 | 7.10 |
| CHEMBL456077 | — | — | 1 | 5.50 |
| CHEMBL498968 | — | — | 1 | 5.29 |
| CHEMBL469437 | — | — | 1 | 4.94 |
| CHEMBL511823 | — | — | 1 | 4.70 |
| CHEMBL449851 | — | — | 1 | - |
| CHEMBL512479 | — | — | 1 | - |
| CHEMBL425308 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL469435 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL456077 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL498968 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL469437 | — | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL511823 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL449851 | — | IC50 | = | 700000.0 | nM | - |
| CHEMBL512479 | — | IC50 | = | 200000.0 | nM | - |
| CHEMBL425308 | — | IC50 | = | 136000.0 | nM | - |