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Assay Detail

CHEMBL1007619

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine liver beta-galactosidase by spectrophotometry
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Beta-galactosidase (CHEMBL3482)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Glycosidase-inhibiting pyrrolidines and pyrrolizidines with a long side chain in Scilla peruviana.
Asano N, Ikeda K, Kasahara M, Arai Y, Kizu H.
J Nat Prod (2004) 67 : 846 -850
PubMed 15165148 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 6.21 7.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL469435 1 7.05
CHEMBL456077 1 5.36
CHEMBL449851 1 -
CHEMBL511823 1 -
CHEMBL512479 1 -
CHEMBL498968 1 -
CHEMBL469437 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL469435 IC50 = 90.0 nM 7.05
CHEMBL456077 IC50 = 4400.0 nM 5.36
CHEMBL449851 IC50 = 260000.0 nM -
CHEMBL511823 IC50 = 130000.0 nM -
CHEMBL512479 IC50 = 320000.0 nM -
CHEMBL498968 IC50 = 830000.0 nM -
CHEMBL469437 IC50 = 920000.0 nM -