Assay Detail
Binding
CHEMBL1007649
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Inhibition of human factor 10a
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Effects of tannins from Geum japonicum on the catalytic activity of thrombin and factor Xa of blood coagulation cascade.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.22 | 6.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL510512 | TELLIMAGRANDIN II | — | 1 | 6.36 |
| CHEMBL509562 | CASUARIIN | — | 1 | 6.35 |
| CHEMBL382408 | PENTAGALLOYL GLUCOSE | — | 1 | 6.24 |
| CHEMBL488110 | — | — | 1 | 6.16 |
| CHEMBL506204 | PEDUNCULAGIN | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL510512 | TELLIMAGRANDIN II | Ki | = | 440.0 | nM | 6.36 |
| CHEMBL509562 | CASUARIIN | Ki | = | 450.0 | nM | 6.35 |
| CHEMBL382408 | PENTAGALLOYL GLUCOSE | Ki | = | 570.0 | nM | 6.24 |
| CHEMBL488110 | — | Ki | = | 690.0 | nM | 6.16 |
| CHEMBL506204 | PEDUNCULAGIN | Ki | = | 990.0 | nM | 6.00 |