Assay Detail
Functional
CHEMBL1007985
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Growth inhibition of human HeLa cells after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Affinity labeling of the proteasome by a belactosin A derived inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.25 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL491637 | — | — | 1 | 6.30 |
| CHEMBL498970 | — | — | 1 | 5.01 |
| CHEMBL491636 | BELACTOSIN A | — | 1 | 4.43 |
| CHEMBL64925 | MG-132 | — | 1 | - |
| CHEMBL490829 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL491637 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL498970 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL491636 | BELACTOSIN A | IC50 | = | 37000.0 | nM | 4.43 |
| CHEMBL64925 | MG-132 | IC50 | - | — | - | |
| CHEMBL490829 | — | IC50 | - | — | - |