Assay Detail
Binding
CHEMBL1008311
Review assay metadata, readout intent, target linkage, and publication context from the same page.
inhibition of human recombinant MMP9 catalytic domain
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and activity of quinolinylmethyl P1' alpha-sulfone piperidine hydroxamate inhibitors of TACE.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.92 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL495831 | — | — | 1 | 4.92 |
| CHEMBL495621 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL495831 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL495621 | — | IC50 | > | 12000.0 | nM | - |