Assay Detail
Binding
CHEMBL1008680
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GST-fused human recombinant Cdc25B2 (275-539) catalytic domain
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Marine sesquiterpenoids that inhibit the lyase activity of DNA polymerase beta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 3 | - | - |
| IC50 | 1 | 4.04 | 4.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL155085 | ILIMAQUINONE | — | 1 | 4.04 |
| CHEMBL484221 | — | — | 1 | - |
| CHEMBL484222 | — | — | 1 | - |
| CHEMBL353955 | DEOXYURIDINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL155085 | ILIMAQUINONE | IC50 | = | 92000.0 | nM | 4.04 |
| CHEMBL484221 | — | Activity | - | — | - | |
| CHEMBL484222 | — | Activity | - | — | - | |
| CHEMBL353955 | DEOXYURIDINE | Activity | - | — | - |