Assay Detail
Functional
CHEMBL1009065
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effect on cardiac activity in guinea pig spontaneously beating heart assessed as change in coronary perfusion pressure
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cavia porcellus |
| Tissue | Heart |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.66 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL23 | DILTIAZEM | 4.0 | 1 | 7.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL23 | DILTIAZEM | EC50 | = | 21.88 | nM | 7.66 |