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Assay Detail

CHEMBL1009870

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Binding
Binding affinity to CB2 receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Cannabinoid receptor 2 (CHEMBL253)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow.
Markt P, Feldmann C, Rollinger JM, Raduner S, Schuster D, Kirchmair J, Distinto S, Spitzer GM, Wolber G, Laggner C, Altmann KH, Langer T, Gertsch J.
J Med Chem (2009) 52 : 369 -378
PubMed 19143566 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 5 8.00 8.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL371214 1 8.47
CHEMBL498767 1 8.14
CHEMBL73711 1 7.92
CHEMBL408430 1 7.82
CHEMBL497392 1 7.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL371214 Ki = 3.4 nM 8.47
CHEMBL498767 Ki = 7.2 nM 8.14
CHEMBL73711 Ki = 12.0 nM 7.92
CHEMBL408430 Ki = 15.1 nM 7.82
CHEMBL497392 Ki = 22.7 nM 7.64