Assay Detail
Binding
CHEMBL1010033
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human GalR2
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 8.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL526003 | GALANTIDE | — | 1 | 9.00 |
| CHEMBL506210 | WTLNSAGYLL | — | 1 | 8.74 |
| CHEMBL503473 | — | — | 1 | 8.70 |
| CHEMBL499179 | — | — | 1 | 8.64 |
| CHEMBL499980 | — | — | 1 | 8.30 |
| CHEMBL2309599 | GALNON | — | 1 | 4.62 |
| CHEMBL503924 | GALMIC TFA | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL526003 | GALANTIDE | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL506210 | WTLNSAGYLL | Kd | = | 1.8 | nM | 8.74 |
| CHEMBL503473 | — | Kd | = | 2.0 | nM | 8.70 |
| CHEMBL499179 | — | Kd | = | 2.3 | nM | 8.64 |
| CHEMBL499980 | — | Kd | = | 5.0 | nM | 8.30 |
| CHEMBL2309599 | GALNON | Kd | = | 24000.0 | nM | 4.62 |
| CHEMBL503924 | GALMIC TFA | Kd | > | 100000.0 | nM | - |