Galanin receptor type 2 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt O43603. Use UniProt O43603 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O43603 as the stable identity anchor, then attach disease evidence before program review.
Galanin receptor type 2
Review this target as Galanin receptor type 2, mapped to UniProt O43603. Sequence length is 387 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Galanin receptor type 2 as ChEMBL target CHEMBL3176, mapped to UniProt O43603. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Galanin receptor type 2 is the right protein anchor across sources, using UniProt O43603 as the stable mapping.
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| Preferred Name | Galanin receptor type 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O43603 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Galanin receptor type 2 |
| UniProt Accession | O43603 |
| Component Type | Protein |
| Sequence Length | 387 aa |
Galanin receptor type 2
Review this target as Galanin receptor type 2, mapped to UniProt O43603. Sequence length is 387 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4128926 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL604373 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL501079 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL501079 | 9.05 | Ki | 0.9 | Preclinical |
| CHEMBL526003 | 9.0 | Kd | 1.0 | Preclinical |
| CHEMBL526003 | 8.96 | Ki | 1.1 | Preclinical |
| CHEMBL592413 | 8.85 | Ki | 1.4 | Preclinical |
| CHEMBL604990 | 8.82 | Ki | 1.5 | Preclinical |
| CHEMBL578710 | 8.76 | Ki | 1.74 | Preclinical |
| CHEMBL503473 | 8.74 | Ki | 1.8 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 52 | 65 | 7.0 |
| cell-based format | 9 | 16 | 7.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 17 | 4.9 |