Assay Detail
Binding
CHEMBL1010034
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Binding affinity to human GalR3
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and characterization of high-affinity, systemically-active galanin analogues with potent anticonvulsant activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 7.22 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL503473 | — | — | 1 | 7.82 |
| CHEMBL526003 | GALANTIDE | — | 1 | 7.40 |
| CHEMBL499179 | — | — | 1 | 7.16 |
| CHEMBL499980 | — | — | 1 | 6.50 |
| CHEMBL506210 | WTLNSAGYLL | — | 1 | - |
| CHEMBL503924 | GALMIC TFA | — | 1 | - |
| CHEMBL2309599 | GALNON | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL503473 | — | Kd | = | 15.0 | nM | 7.82 |
| CHEMBL526003 | GALANTIDE | Kd | = | 40.0 | nM | 7.40 |
| CHEMBL499179 | — | Kd | = | 69.0 | nM | 7.16 |
| CHEMBL499980 | — | Kd | = | 315.0 | nM | 6.50 |
| CHEMBL506210 | WTLNSAGYLL | Kd | - | — | - | |
| CHEMBL503924 | GALMIC TFA | Kd | - | — | - | |
| CHEMBL2309599 | GALNON | Kd | - | — | - |