Assay Detail
Binding
CHEMBL1010666
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Trypanosoma brucei G6PDH using glucose-6-phosphate as substrate by Lineweaver-Burke plot
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma brucei |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glucose-6-phosphate 1-dehydrogenase (CHEMBL5672) ↗| Type | SINGLE PROTEIN |
| Organism | Trypanosoma brucei |
Publication
Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.04 | 6.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL272195 | EPIANDROSTERONE | — | 1 | 6.31 |
| CHEMBL90593 | PRASTERONE | 4.0 | 1 | 5.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL272195 | EPIANDROSTERONE | Ki | = | 490.0 | nM | 6.31 |
| CHEMBL90593 | PRASTERONE | Ki | = | 1700.0 | nM | 5.77 |