Assay Detail
Binding
CHEMBL1013319
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Displacement of radioligand from rat alpha1 adrenergic receptor by liquid scintillation spectrometry
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Perhydrogenation of tabersonine, ans Aspidiosperma indole alkaloid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.88 | 8.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1558 | PRAZOSIN HYDROCHLORIDE | 4.0 | 1 | 8.46 |
| CHEMBL509387 | — | — | 1 | 5.29 |
| CHEMBL453023 | — | — | 1 | - |
| CHEMBL3216651 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1558 | PRAZOSIN HYDROCHLORIDE | Ki | = | 3.5 | nM | 8.46 |
| CHEMBL509387 | — | Ki | = | 5100.0 | nM | 5.29 |
| CHEMBL453023 | — | Ki | > | 100000.0 | nM | - |
| CHEMBL3216651 | — | Ki | > | 100000.0 | nM | - |