Assay Detail
Functional
CHEMBL1013430
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Cytotoxicity against mouse 3LL cells by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | 3LL |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and characterization of Deltalac-acetogenins that potently inhibit mitochondrial complex I.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.95 | 6.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL503220 | — | — | 1 | 6.32 |
| CHEMBL498986 | — | — | 1 | 6.19 |
| CHEMBL464549 | dleta-lac-Acetogenin | — | 1 | 6.00 |
| CHEMBL457770 | — | — | 1 | 5.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL503220 | — | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL498986 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL464549 | dleta-lac-Acetogenin | IC50 | = | 990.0 | nM | 6.00 |
| CHEMBL457770 | — | IC50 | = | 5200.0 | nM | 5.28 |