Assay Detail
Binding
CHEMBL1013539
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Binding affinity to galectin 1 at 20 degC by fluorescence polarization assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 8 | 4.88 | 5.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL509915 | — | — | 1 | 5.36 |
| CHEMBL458489 | — | — | 1 | 5.19 |
| CHEMBL505576 | — | — | 1 | 4.99 |
| CHEMBL443156 | — | — | 1 | 4.83 |
| CHEMBL509180 | — | — | 1 | 4.78 |
| CHEMBL52011 | THIODIGALACTOSIDE | — | 1 | 4.11 |
| CHEMBL457432 | — | — | 1 | - |
| CHEMBL5314358 | LACTOSE, ANHYDROUS | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL509915 | — | Kd | = | 4400.0 | nM | 5.36 |
| CHEMBL458489 | — | Kd | = | 6400.0 | nM | 5.19 |
| CHEMBL505576 | — | Kd | = | 10300.0 | nM | 4.99 |
| CHEMBL443156 | — | Kd | = | 14700.0 | nM | 4.83 |
| CHEMBL509180 | — | Kd | = | 16800.0 | nM | 4.78 |
| CHEMBL52011 | THIODIGALACTOSIDE | Kd | = | 78000.0 | nM | 4.11 |
| CHEMBL457432 | — | Kd | = | 150000.0 | nM | - |
| CHEMBL5314358 | LACTOSE, ANHYDROUS | Kd | = | 420000.0 | nM | - |