Assay Detail
Binding
CHEMBL1013541
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Binding affinity to galectin 1 at 0 degC by fluorescence polarization assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 4.93 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL503116 | — | — | 1 | 5.70 |
| CHEMBL444662 | — | — | 1 | 5.02 |
| CHEMBL457430 | — | — | 1 | 4.85 |
| CHEMBL516152 | — | — | 1 | 4.60 |
| CHEMBL457221 | — | — | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL503116 | — | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL444662 | — | Kd | = | 9600.0 | nM | 5.02 |
| CHEMBL457430 | — | Kd | = | 14000.0 | nM | 4.85 |
| CHEMBL516152 | — | Kd | = | 25000.0 | nM | 4.60 |
| CHEMBL457221 | — | Kd | = | 35000.0 | nM | 4.46 |