Assay Detail
Binding
CHEMBL1014332
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to mu opioid receptor in rat brain membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Ligand binding to nucleic acids and proteins: Does selectivity increase with strength?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.38 | 7.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL567175 | NALTRINDOLE | — | 1 | 7.57 |
| CHEMBL401093 | OXYMORPHINDOLE | — | 1 | 7.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL567175 | NALTRINDOLE | Ki | = | 27.0 | nM | 7.57 |
| CHEMBL401093 | OXYMORPHINDOLE | Ki | = | 66.0 | nM | 7.18 |