Assay Detail
Functional
CHEMBL1014407
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Cytotoxicity against human UACC-903 cells after 72 hrs by MTS assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | UACC-903 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.85 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL461455 | PHENYLHEXYL ISOSELENOCYANATE | — | 1 | 5.00 |
| CHEMBL443508 | PHENYLBUTYL ISOSELENOCYANATE | — | 1 | 5.00 |
| CHEMBL442870 | PHENETHYLISOSELENOCYANATE | — | 1 | 4.92 |
| CHEMBL151649 | PHENETHYLISOTHIOCYANATE | — | 1 | 4.92 |
| CHEMBL55285 | BENZYL ISOTHIOCYANATE | — | 1 | 4.82 |
| CHEMBL461242 | PHENYLHEXYL ISOTHIOCYANATE | — | 1 | 4.82 |
| CHEMBL447807 | BENZYLISOSELENOCYANATE | — | 1 | 4.80 |
| CHEMBL446473 | PHENYLBUTYL ISOTHIOCYANATE | — | 1 | 4.80 |
| CHEMBL459763 | — | — | 1 | 4.77 |
| CHEMBL512562 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL461455 | PHENYLHEXYL ISOSELENOCYANATE | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL443508 | PHENYLBUTYL ISOSELENOCYANATE | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL442870 | PHENETHYLISOSELENOCYANATE | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL151649 | PHENETHYLISOTHIOCYANATE | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL55285 | BENZYL ISOTHIOCYANATE | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL461242 | PHENYLHEXYL ISOTHIOCYANATE | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL447807 | BENZYLISOSELENOCYANATE | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL446473 | PHENYLBUTYL ISOTHIOCYANATE | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL459763 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL512562 | — | IC50 | = | 24000.0 | nM | 4.62 |