Assay Detail

CHEMBL1015615

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Functional

Antiviral activity against HIV1 in cell cultures assessed as inhibition of viral replication

ChEMBL ↗

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Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

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Primary target Human immunodeficiency virus 1

CHEMBL378

Anchored from Assay target.

Protein identity Human immunodeficiency virus 1

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Human immunodeficiency virus 1
Confidence	1 — Organism
Curated By	Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378) ↗

Type	ORGANISM
Organism	Human immunodeficiency virus 1

Publication

Synthesis and structure-activity relationship study of lamellarin derivatives.

Ishibashi F, Tanabe S, Oda T, Iwao M.
J Nat Prod (2002) 65 : 500 -504
PubMed 11975488 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.10	5.10

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL505948	—	—	1	5.10

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL505948	—	IC50	=	8000.0	nM	5.10