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Assay Detail

CHEMBL1016812

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of EGFR
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Epidermal growth factor receptor (CHEMBL203)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

2,3-Disubstituted 8-arylamino-3H-imidazo[4,5-g]quinazolines: a novel class of antitumor agents.
Zhang Y, Chen Z, Lou Y, Yu Y.
Eur J Med Chem (2009) 44 : 448 -452
PubMed 18313807 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 10.60 10.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL29197 1 10.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL29197 IC50 = 0.025 nM 10.60