Assay Detail
Binding
CHEMBL1017822
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FYN Val285Cys mutant expressed in Escherichia coli
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Structural bioinformatics-based design of selective, irreversible kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL515414 | — | — | 1 | 9.00 |
| CHEMBL515416 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL515414 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL515416 | — | IC50 | = | 100.0 | nM | 7.00 |