Assay Detail
ADMET
CHEMBL1019159
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human CEM-SS cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | CEM-SS |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-HIV and cytotoxic alkaloids from Buchenavia capitata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.71 | 6.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL489967 | — | — | 1 | 6.18 |
| CHEMBL490159 | BUCHENAVIANINE | — | 1 | 5.24 |
| CHEMBL523951 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL489967 | — | IC50 | = | 660.0 | nM | 6.18 |
| CHEMBL490159 | BUCHENAVIANINE | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL523951 | — | IC50 | = | 142000.0 | nM | - |