Assay Detail
ADMET
CHEMBL1021189
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Cytostatic activity against human WI38 cells after 72 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: synthesis, cytostatic and antiviral activity evaluations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.69 | 4.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL455791 | — | — | 1 | 4.80 |
| CHEMBL506356 | — | — | 1 | 4.75 |
| CHEMBL460116 | — | — | 1 | 4.70 |
| CHEMBL463071 | — | — | 1 | 4.68 |
| CHEMBL460327 | — | — | 1 | 4.52 |
| CHEMBL474168 | — | — | 1 | - |
| CHEMBL474169 | — | — | 1 | - |
| CHEMBL468947 | — | — | 1 | - |
| CHEMBL25725 | — | — | 1 | - |
| CHEMBL460110 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL455791 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL506356 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL460116 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL463071 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL460327 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL474168 | — | IC50 | - | — | - | |
| CHEMBL474169 | — | IC50 | - | — | - | |
| CHEMBL468947 | — | IC50 | - | — | - | |
| CHEMBL25725 | — | IC50 | - | — | - | |
| CHEMBL460110 | — | IC50 | - | — | - |